drugset / Trial / NCT00003072

Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer

NCT00003072

Phase 2 Completed 80 enrolled University of California, San Francisco
Supportive care

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving the drugs in different combinations may kill more tumor cells. PURPOSE: Randomized phase II double-blinded trial to study the effectiveness of paclitaxel and carboplatin given with either amifostine or placebo in patients with metastatic stage III or stage IV ovarian cancer or metastatic stage III or stage IV non-small cell lung cancer.

Timeline

Start
1997-05
Primary completion
1998-10
Completion
1998-10

Drugs

EvaluationDrugModalityDoseRoute
Subject amifostine Unknown Intravenous
Background Carboplatin Small molecule
Background Paclitaxel Small molecule Intravenous