drugset / Trial / NCT00003099
Chemoprevention Therapy Plus Surgery in Treating Women With Breast Cancer
RandomizedSingle-groupOpen-labelPrevention
Summary
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of fenretinide and tamoxifen before surgery may be an effective way to prevent the recurrence of or further development of breast cancer. PURPOSE: Randomized phase II trial to study the effectiveness of fenretinide and tamoxifen given before surgery in treating women with breast cancer.
Timeline
- Start
- 1996-05
- Primary completion
- 2000-06
- Completion
- 2003-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tamoxifen | Small molecule | — | — |
| Comparator | fenretinide | Small molecule | — | — |