drugset / Trial / NCT00003099

Chemoprevention Therapy Plus Surgery in Treating Women With Breast Cancer

NCT00003099

RandomizedSingle-groupOpen-labelPrevention

Summary

RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of fenretinide and tamoxifen before surgery may be an effective way to prevent the recurrence of or further development of breast cancer. PURPOSE: Randomized phase II trial to study the effectiveness of fenretinide and tamoxifen given before surgery in treating women with breast cancer.

Timeline

Start
1996-05
Primary completion
2000-06
Completion
2003-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tamoxifen Small molecule
Comparator fenretinide Small molecule

Indications