drugset / Trial / NCT00003601
Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus Syndrome
Phase 2
Completed
38 enrolled
Eastern Cooperative Oncology Group
National Cancer Institute (NCI) · collab
RandomizedPrevention
Summary
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of tretinoin and/or fenretinide may be an effective way to prevent the recurrence or further development of dysplastic nevus syndrome. PURPOSE: Randomized phase II trial to compare the effectiveness of tretinoin with or without fenretinide in treating patients with dysplastic nevus syndrome.
Timeline
- Start
- 1999-02-23
- Primary completion
- 2000-03
- Completion
- 2004-03-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tretinoin | Small molecule | — | Topical |
| Subject | fenretinide | Small molecule | — | Oral |