drugset / Trial / NCT00003715
Vaccine Therapy Compared With Interferon Alfa in Treating Patients With Stage III Melanoma
RandomizedTreatment
Summary
RATIONALE: Vaccines made from a person's melanoma cells may make the body build an immune response to kill tumor cells. Interferon alfa may interfere with the growth of the cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of melanoma vaccine with that of interferon alfa-2b in treating patients who have stage III melanoma that has spread to regional lymph nodes following surgery.
Timeline
- Start
- 1998-12
- Primary completion
- —
- Completion
- —
Outcome
Outcome not reported
Stopped (Enrollment): “Terminated: recruiting or enrolling participants has halted prematurely and will not resume; participants are no longer being examined or treated”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | autologous tumor cell vaccine | Vaccine | — | Other |
| Subject | recombinant interferon alfa | Protein / enzyme biologic | — | Intravenous |
| Background | BCG vaccine | Vaccine | — | — |
| Background | Cyclophosphamide | Other / unclassified | — | — |