drugset / Trial / NCT00003754
Thalidomide and Cyclophosphamide in Treating Children With Recurrent or Refractory Childhood Cancers
Treatment
Summary
RATIONALE: Thalidomide may kill tumor cells by stopping the growth of new blood vessels to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining thalidomide with chemotherapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining thalidomide and cyclophosphamide in treating children who have recurrent or refractory childhood cancers.
Timeline
- Start
- 1998-09
- Primary completion
- 2001-07
- Completion
- 2001-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Subject | Thalidomide | Other / unclassified | — | Oral |