drugset / Trial / NCT00004215
Leridistim Compared With Filgrastim in Treating Older Patients With Acute Myeloid Leukemia
RandomizedSupportive care
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Colony-stimulating factors such as leridistim and filgrastim increase the number of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. PURPOSE: Randomized phase II trial to compare the effectiveness of leridistim with that of filgrastim to reduce side effects in older patients who are receiving cytarabine and daunorubicin for acute myeloid leukemia.
Timeline
- Start
- 1999-08
- Primary completion
- 2000-08
- Completion
- 2000-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | filgrastim | Protein / enzyme biologic | — | Subcutaneous |
| Subject | leridistim | Protein / enzyme biologic | — | Subcutaneous |
| Background | Cytarabine | Small molecule | — | Intravenous |
| Background | Daunorubicin | Small molecule | — | Intravenous |