drugset / Trial / NCT00004297
Phase III Randomized Study of Diazepam Vs Lorazepam Vs Placebo for Prehospital Treatment of Status Epilepticus
Phase 3
Completed
210 enrolled
National Institute of Neurological Disorders and Stroke (NINDS)
University of California, San Francisco · collab
RandomizedDouble-blindTreatment
Summary
OBJECTIVES: I. Compare the efficacy, onset of clinical anticonvulsant activity, and complications of diazepam and lorazepam given intravenously as prehospital therapy to patients in status epilepticus. II. Determine the effect of prehospital therapy on the incidence of status epilepticus at the subsequent emergency department admission. III. Establish whether prehospital therapy alters hospital management of these patients and ultimately affects patient outcome.
Timeline
- Start
- 1995-11
- Primary completion
- —
- Completion
- 1999-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Diazepam | Small molecule | — | Intravenous |
| Subject | Lorazepam | Small molecule | — | Intravenous |
Indications
No indication recorded.