drugset / Trial / NCT00004323
Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia
Phase 2
Completed
10 enrolled
National Center for Research Resources (NCRR)
University of California, Los Angeles · collab
Treatment
Summary
OBJECTIVES: I. Evaluate the efficacy of related, HLA-identical bone marrow transplantation following cyclophosphamide (CTX) and antithymocyte globulin in patients with aplastic anemia. II. Evaluate the efficacy of related, HLA-nonidentical bone marrow transplantation following CTX and total-body irradiation/total-lymphoid irradiation in patients with aplastic anemia.
Timeline
- Start
- 1995-02
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | 2-MERCAPTOETHANESULFONIC ACID | Small molecule | — | — |
| Background | ANTILYMPHOCYTE IMMUNOGLOBULIN (HORSE) | Protein / enzyme biologic | — | — |
| Background | Cyclophosphamide | Other / unclassified | — | — |
| Background | Cyclosporine | Peptide | — | — |
| Background | Methotrexate | Small molecule | — | — |
| Background | Methylprednisolone | Other / unclassified | — | — |