drugset / Trial / NCT00005030
SCH 66336 Before Surgery in Treating Patients With Colorectal Cancer That Has Metastasized to the Liver
RandomizedSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Randomized phase I trial to compare the effectiveness of different doses of SCH 66336 before surgery in treating patients who have colorectal cancer that has metastasized to the liver.
Timeline
- Start
- 1999-09-29
- Primary completion
- 2000-09
- Completion
- 2000-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lonafarnib | Small molecule | 100 mg | Oral |
| Subject | Lonafarnib | Small molecule | 200 mg | Oral |
| Subject | Lonafarnib | Small molecule | 300 mg | Oral |