drugset / Trial / NCT00005604

Interleukin-12 Plus Interleukin-2 in Treating Patients With Advanced Solid Tumors

NCT00005604

Phase 1 Completed 25 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Phase I trial to study the effectiveness of interleukin-12 plus interleukin-2 in treating patients who have advanced solid tumors. Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person's white blood cells to kill cancer cells. Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. Combining the two drugs may kill more cancer cells

Timeline

Start
2000-03
Primary completion
2003-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject aldesleukin Protein / enzyme biologic Subcutaneous
Subject interleukin-12 Protein / enzyme biologic Intravenous