drugset / Trial / NCT00005961

O6-benzylguanine and Carmustine in Treating Patients With Unresectable Locally Recurrent or Metastatic Melanoma

NCT00005961

Phase 2 Completed 40 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Phase II trial to study the effectiveness of O6-benzylguanine and carmustine in treating patients who have unresectable locally recurrent or metastatic melanoma. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than once chemotherapy drug may kill more tumor cells.

Timeline

Start
2000-06
Primary completion
2005-12
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject O6-benzylguanine Small molecule Intravenous
Subject carmustine Small molecule Intravenous

Indications