drugset / Trial / NCT00006095
Combination Chemotherapy in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of vincristine plus irinotecan in treating children who have solid tumors that have not responded to previous therapy.
Timeline
- Start
- 2000-07
- Primary completion
- 2005-01
- Completion
- 2005-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Irinotecan | Small molecule | — | Intravenous |
| Subject | Vincristine | Small molecule | 1.5 mg/m2 | Intravenous |
| Subject | Vincristine | Small molecule | 2 mg/m2 | Intravenous |