drugset / Trial / NCT00006133
Randomized Study of Oral Contraceptives or Hormone Replacement Therapy in Women With Systemic Lupus Erythematosus
Completed
970 enrolled
National Center for Research Resources (NCRR)
University of Alabama at Birmingham · collab
RandomizedDouble-blindTreatment
Summary
OBJECTIVES: I. Determine the effect of oral contraceptives containing low-dose synthetic estrogens and progestins on disease activity in premenopausal women with inactive, stable, or moderate systemic lupus erythematosus (SLE). II. Determine the effect of hormone replacement therapy with conjugated estrogens and progestins on disease activity in postmenopausal women with inactive, stable, or moderate SLE.
Timeline
- Start
- 2000-06
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Estradiol | Other / unclassified | — | Oral |
| Subject | Norethindrone | Unknown | — | Oral |
| Subject | ethinyl estradiol | Small molecule | — | Oral |
| Subject | medroxyprogesterone acetate | Other / unclassified | — | Oral |