drugset / Trial / NCT00008047

Combination Chemotherapy Combined With Radiation Therapy in Treating Patients Who Have Stage II or Stage III Cancer of the Esophagus

NCT00008047

RandomizedOpen-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining more than one chemotherapy drug with radiation therapy may kill more tumor cells. PURPOSE: Randomized phase I/II trial to study the effectiveness of combination chemotherapy with or without paclitaxel combined with radiation therapy in treating patients who have stage II or stage III cancer of the esophagus.

Timeline

Start
1999-08
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydroxyurea Other / unclassified Oral
Subject Paclitaxel Small molecule Intravenous
Subject fluorouracil Small molecule Intravenous

Indications