drugset / Trial / NCT00017459

Cisplatin Plus Vinorelbine With or Without Tirapazamine in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

NCT00017459

Phase 3 Completed Sanofi
Treatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if cisplatin and vinorelbine are more effective with or without tirapazamine in treating non-small cell lung cancer PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin plus vinorelbine with or without tirapazamine in treating patients who have stage IIIB or stage IV non-small cell lung cancer.

Timeline

Start
2000-07
Primary completion
Completion
2004-02

Drugs

EvaluationDrugModalityDoseRoute
Subject tirapazamine Small molecule Intravenous
Background Cisplatin Other / unclassified Intravenous
Background Vinorelbine Small molecule Intravenous

Indications