drugset / Trial / NCT00017641

Phase I Study of Immune Ablation and CD34+ Peripheral Blood Stem Cell Support in Patients With Systemic Lupus Erythematosus

NCT00017641

Phase 1 Unknown 10 enrolled Northwestern Memorial Hospital
Treatment

Summary

OBJECTIVES: I. Determine the safety of immune ablation with high-dose cyclophosphamide and anti-thymocyte globulin followed by peripheral blood stem cell support in patients with systemic lupus erythematosus.

Timeline

Start
2001-04
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject ANTILYMPHOCYTE IMMUNOGLOBULIN (HORSE) Protein / enzyme biologic Intravenous
Subject Cyclophosphamide Other / unclassified Intravenous
Background filgrastim Protein / enzyme biologic Subcutaneous