drugset / Trial / NCT00019058

Radiation Therapy in Treating Patients With Glioblastoma

NCT00019058

Phase 1 Completed 34 enrolled National Cancer Institute (NCI)
Treatment

Summary

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as pentoxifylline and hydroxyurea may make tumor cells more sensitive to radiation therapy. PURPOSE: Phase I trial to study the effectiveness of radiation therapy plus pentoxifylline and hydroxyurea in treating patients who have high-grade astrocytoma or glioblastoma.

Timeline

Start
1995-04
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Pentoxifylline Small molecule Intravenous
Background Hydroxyurea Other / unclassified