drugset / Trial / NCT00019214

Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma

NCT00019214

Phase 1/2 Completed National Cancer Institute (NCI)
Treatment

Summary

RATIONALE: Vaccines made from white blood cells treated with antigens may make the body build an immune response to kill melanoma cells. Interleukin-2 may stimulate a person's white blood cells to kill tumor cells. Combining vaccine therapy with interleukin-2 may kill more melanoma cells. PURPOSE: This phase I/II trial is studying the side effects and how well giving vaccine therapy and interleukin-2 works compared to vaccine therapy alone in treating patients with metastatic melanoma that has not responded to previous therapy.

Timeline

Start
1997-04
Primary completion
Completion
2006-07

Drugs

EvaluationDrugModalityDoseRoute
Subject MART-1 antigen Vaccine Other
Subject aldesleukin Protein / enzyme biologic Subcutaneous
Subject gp100 antigen Peptide Other

Indications