drugset / Trial / NCT00019396

flt3L With or Without Vaccine Therapy in Treating Patients With Metastatic Melanoma or Renal Cell Cancer

NCT00019396

Treatment

Summary

RATIONALE: The drug flt3L may stimulate a person's immune system and help to kill tumor cells. Vaccines made from melanoma cells may make the body build an immune response to and kill their tumor cells. PURPOSE: Phase II trial to study the effectiveness of flt3L with or without vaccine therapy in treating patients with metastatic melanoma or renal cell cancer.

Timeline

Start
1998-02
Primary completion
Completion
2007-03

Drugs

EvaluationDrugModalityDoseRoute
Subject MART-1 antigen Vaccine Subcutaneous
Subject flt3 ligand Protein / enzyme biologic Subcutaneous
Subject gp100:209-217 Peptide Subcutaneous
Subject gp100:280-288 Peptide Subcutaneous
Subject tyrosinase peptide Peptide Subcutaneous
Background incomplete Freund's adjuvant Other / unclassified Subcutaneous