drugset / Trial / NCT00021073

Combination Chemotherapy in Treating Patients With Advanced Cancer

NCT00021073

Phase 1 Completed 90 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Phase I trial to study the effectiveness of combining flavopiridol, fluorouracil, and leucovorin with or without irinotecan in treating patients who have advanced cancer. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.

Timeline

Start
2001-05
Primary completion
2006-04
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule Intravenous
Subject Leucovorin Small molecule Intravenous
Subject alvocidib Small molecule Intravenous
Subject fluorouracil Small molecule Intravenous