Bortezomib and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Summary

Phase I trial to study the effectiveness of combining bortezomib with paclitaxel in treating patients who have advanced or metastatic solid tumors. Bortezomib may stop the growth of cancer cells by blocking the enzymes necessary for their growth. Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Combining bortezomib with paclitaxel may kill more tumor cells.

Timeline

Start

2001-11

Primary completion

2009-02

Completion

—

Drugs

Indications