Paclitaxel Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Paclitaxel may make the tumor cells more sensitive to radiation therapy. PURPOSE: Phase I trial to study the effectiveness of combining paclitaxel with radiation therapy in treating children who have newly diagnosed brain stem glioma.

Timeline

Start

1999-08

Primary completion

2006-09

Completion

2006-09

Outcome

Outcome not reported

Stopped (Enrollment): “Administrative closure 9/22/2006. Decline in enrollment at CHOP. due to competing protocols with new agents.”

Drugs

Indications