drugset / Trial / NCT00035295
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-061)
RandomizedParallel-groupDouble-blindTreatment
Summary
A clinical study to determine the efficacy and safety of an Treatment of MK0869 in the treatment of depression.
Timeline
- Start
- 2001-11-08
- Primary completion
- 2003-12-05
- Completion
- 2003-12-05
Publications
- Background Keller M, Montgomery S, Ball W, Morrison M, Snavely D, Liu G, Hargreaves R, Hietala J, Lines C, Beebe K, Reines S. Lack of efficacy of the substance p (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder. Biol Psychiatry. 2006 Feb 1;59(3):216-23. doi: 10.1016/j.biopsych.2005.07.013. Epub 2005 Oct 24.
- Background Liu KS, Snavely DB, Ball WA, Lines CR, Reines SA, Potter WZ. Is bigger better for depression trials? J Psychiatr Res. 2008 Jul;42(8):622-30. doi: 10.1016/j.jpsychires.2007.07.003. Epub 2007 Sep 7.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aprepitant | Other / unclassified | — | — |