drugset / Trial / NCT00037102
Combination Therapy With Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis
Phase 4
Completed
16 enrolled
MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute
Biogen · collabConsultants in Neurology · collab
NaSingle-groupOpen-labelTreatment
Summary
The participant will receive weekly intramuscular treatment with AVONEX® (interferon beta 1-a) and bi-monthly high dose intravenous methotrexate with Leucovorin rescue.
Timeline
- Start
- 2001-07
- Primary completion
- 2003-12
- Completion
- 2003-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Interferon beta-1a | Protein / enzyme biologic | 30 ug | Intramuscular |
| Subject | Methotrexate | Small molecule | 2000 mg/m2 | Intravenous |