drugset / Trial / NCT00042874

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

NCT00042874

Phase 1 Completed 77 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. This phase I trial is studying the side effects and best dose of combination chemotherapy in treating patients with locally advanced or metastatic solid tumors.

Timeline

Start
2002-05
Primary completion
2009-01
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject alvocidib Small molecule Intravenous
Subject fluorouracil Small molecule Intravenous
Background Irinotecan Small molecule Intravenous
Background Leucovorin Small molecule Intravenous