Marijuana for HIV-Related Peripheral Neuropathy

Summary

To evaluate whether smoked marijuana reduces pain in people with HIV-related peripheral neuropathy.

Timeline

Start

2003-01

Primary completion

—

Completion

2005-04

Outcome

Met primary endpoint

paper Smoked cannabis reduced daily pain by 34% (median reduction; IQR = -71, -16) vs 17% (IQR = -29, 8) with placebo (p = 0.03). PMID 17296917 ↗

paper Greater than 30% reduction in pain was reported by 52% in the cannabis group and by 24% in the placebo group (p = 0.04). PMID 17296917 ↗

Publications

• Results Abrams DI, Jay CA, Shade SB, Vizoso H, Reda H, Press S, Kelly ME, Rowbotham MC, Petersen KL. Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial. Neurology. 2007 Feb 13;68(7):515-21. doi: 10.1212/01.wnl.0000253187.66183.9c.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cannabis	Traditional medicine (herbal / TCM)	3.56 %	Other

Indications