Drugs / Cannabis
last change 10 days ago re-read 9 days ago

Cannabis

Traditional medicine (herbal / TCM)

Developed for
cannabis dependence · neuropathy, painful · psychiatric disorder · multiple sclerosis · chronic pain syndrome · HIV infectious disease · spinal cord injury · substance-related disorder
+26 more · acute opioid poisoning · anxiety · cardiovascular disorder · complex regional pain syndrome type 1 · diabetic polyneuropathy · myofascial pain syndrome · neoplasm · obesity disorder · obsessive-compulsive disorder · osteoarthritis, knee · peripheral nervous system disorder · postherpetic neuralgia · psoriatic arthritis · retinitis pigmentosa · schizophrenia · sickle cell disease · sleep disorder · spondylosis, cervical · temporomandibular joint disorder · tinnitus · Tourette syndrome · chronic obstructive pulmonary disease · Crohn disease · lung cancer · peripheral neuropathy · ulcerative colitis
Investigated by
National Institute on Drug Abuse (NIDA) · New York State Psychiatric Institute · Center for Medicinal Cannabis Research · Johns Hopkins University · University of California, San Francisco · Shanna Babalonis, PhD
+70 more · Centre for Addiction and Mental Health · Research Foundation for Mental Hygiene, Inc. · University of California, San Diego · Yale University · National Highway Traffic Safety Administration (NHTSA) · RTI International · Battelle Memorial Institute · Brown University · Hartford Hospital · Massachusetts General Hospital · National Institutes of Health (NIH) · Substance Abuse and Mental Health Services Administration (SAMHSA) · University Health Network, Toronto · University of California, Los Angeles · Acclaro Research Solutions, Inc. · Advanced Brain Monitoring, Inc. · Algorithme Pharma Inc · Alkermes, Inc. · American Association of Sensory Electrodiagnostic Medicine · Bayliss J. Camp, PhD · Biopharmacy, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland · Cambridge Health Alliance · Cognitive Research Corporation · Columbia University · Dalhousie University · Dartmouth-Hitchcock Medical Center · Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland · Food and Drug Administration (FDA) · Gary R Gaffney · Hadassah Medical Organization · Hannah Harris · Harley Street (CPC) Limited · Harvard Medical School (HMS and HSDM) · Hebrew University of Jerusalem · Institute of Forensic Medicine, University of Basel, Basel, Switzerland · Jamie Burr · Khon Kaen University · Kite Systems · London Metropolitan University · Maastricht University · MaineHealth · Massachusetts Institute of Technology · McGill University Health Centre/Research Institute of the McGill University Health Centre · Medical University of Silesia · Nathan Kline Institute for Psychiatric Research · National Heart, Lung, and Blood Institute (NHLBI) · National Institute of General Medical Sciences (NIGMS) · Pippa Hawley · Prairie Plant Systems Inc. · Rambam Health Care Campus · Research Institute of the McGill University Health Center · Roswell Park Cancer Institute · TO Pharmaceuticals · Theodore Brasky PhD · Timothy L. Brown · U.S. Department of Justice · Unity Health Toronto · University Psychiatric Clinics Basel · University of Arkansas · University of Basel · University of California, Davis · University of Colorado, Denver · University of Iowa · University of Kentucky · University of Kentucky · University of Minnesota · University of Vermont · VA Northern California Health Care System · Washington State University · Wolfson Medical Center

Trials 95 · started per year

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 07 trials
Phase 0 NCT07434895 Jul 2026 → Dec 2029 expected substance abuse Hannah Harris Recruiting No outcome recorded
Phase 0 NCT04693884 Sep 2021 → Apr 2025 — Jamie Burr Completed No outcome recorded
Phase 0 NCT04856566 Jul 2021 → Aug 2023 alcohol-induced mental disorder Yale University Completed No outcome recorded
Phase 0 NCT04982965 May 2021 → Jan 2027 expected intervertebral disk degenerative disorder, radiculopathy, sciatica University of California, San Diego Recruiting No outcome recorded
Phase 0 NCT03994926 Feb → Mar 2020 psychiatric disorder Battelle Memorial Institute Terminated No outcome recorded
Phase 0 NCT03078309 Sep 2018 → Dec 2021 retinitis pigmentosa Hadassah Medical Organization Unknown No outcome recorded
Phase 0 NCT02817698 Nov 2017 → Jan 2022 cannabis dependence Yale University Completed No outcome recorded
Phase 132 trials · 1 missed
Phase 1 NCT07661446 Nov 2026 → Jul 2029 expected cannabis dependence, opiate dependence University of Kentucky Not yet recruiting No outcome recorded
Phase 1 NCT07214155 Sep 2026 → Jun 2029 expected psychiatric disorder Johns Hopkins University Recruiting No outcome recorded
Phase 1 NCT06351540 Aug 2026 → Jul 2027 expected cognitive disorder Johns Hopkins University Not yet recruiting No outcome recorded
Phase 1 NCT06055231 Aug 2026 → Mar 2027 expected lung carcinoma Roswell Park Cancer Institute Not yet recruiting No outcome recorded
Phase 1 NCT07668635 Jul 2026 → Jul 2030 expected substance-related disorder Shanna Babalonis, PhD Not yet recruiting No outcome recorded
Phase 1 NCT06055309 May → Dec 2025 — University of Arkansas Completed No outcome recorded
Phase 1 NCT05865470 Apr 2025 → Oct 2028 expected poisoning, substance abuse University of California, Los Angeles Recruiting No outcome recorded
Phase 1 NCT06293040 Sep 2024 → Aug 2027 expected alcohol-related disorders Johns Hopkins University Recruiting No outcome recorded
Phase 1 NCT05729932 Sep 2024 → Jun 2027 expected substance-related disorder Shanna Babalonis, PhD Recruiting No outcome recorded
Phase 1 NCT05602649 Jul 2024 → Jan 2027 expected — Johns Hopkins University Recruiting No outcome recorded
Phase 1/217 trials · 2 met primary · 1 missed
Phase 1/2 NCT07658677 Sep 2026 → Jul 2027 expected cancer, hematopoietic and lymphoid system neoplasm Theodore Brasky PhD Not yet recruiting No outcome recorded
Phase 1/2 NCT05273658 Aug 2022 → Jun 2023 alcohol-related disorders University of California, San Diego Withdrawn No outcome recorded Stop: Business
Phase 1/2 NCT05116527 Jul 2022 → Dec 2025 — Hartford Hospital Unknown No outcome recorded
Phase 1/2 NCT03274440 Oct 2017 → Mar 2019 obsessive-compulsive disorder New York State Psychiatric Institute Completed No outcome recorded
Phase 1/2 NCT02849587 Feb 2017 → Jun 2019 psychiatric disorder University of California, San Diego Completed Met primary
Phase 1/2 NCT03251326 Oct 2015 → Jun 2019 cannabis dependence, post-traumatic stress disorder New York State Psychiatric Institute Terminated No outcome recorded Stop: Enrollment
Phase 1/2 NCT01771731 Aug 2014 → May 2017 sickle cell disease University of California, San Francisco Completed Missed primary
Phase 1/2 NCT01037088 Dec 2009 → Nov 2012 complex regional pain syndrome type 1, multiple sclerosis, neuropathy, painful, postherpetic neuralgia +1 University of California, Davis Completed No outcome recorded
Phase 1/2 NCT00781001 Jul 2008 → Jun 2011 diabetic polyneuropathy Center for Medicinal Cannabis Research Completed No outcome recorded
Phase 1/2 NCT00254761 Nov 2003 → Feb 2006 neuropathy, painful Center for Medicinal Cannabis Research Completed No outcome recorded
Phase 224 trials · 1 met primary · 1 missed
Phase 2 NCT05563948 Oct 2026 → Sep 2032 — New York State Psychiatric Institute Suspended No outcome recorded
Phase 2 NCT06137365 Jul 2026 → Mar 2028 expected obesity disorder University of Kentucky Not yet recruiting No outcome recorded
Phase 2 NCT07216690 Apr 2026 → Jan 2028 expected psychiatric disorder Johns Hopkins University Recruiting No outcome recorded
Phase 2 NCT05999383 Jul 2025 → Feb 2028 expected — University of California, San Francisco Recruiting No outcome recorded
Phase 2 NCT06059677 Oct 2023 → Dec 2024 — Bayliss J. Camp, PhD Unknown No outcome recorded
Phase 2 NCT05488509 Aug 2023 → May 2025 — Washington State University Completed No outcome recorded
Phase 2 NCT04269993 May 2022 → Jul 2023 psoriatic arthritis Brown University Terminated No outcome recorded Stop: Business
Phase 2 NCT05114460 Nov 2021 → Oct 2024 acute opioid poisoning New York State Psychiatric Institute Terminated No outcome recorded Stop: Enrollment
Phase 2 NCT04596644 Aug 2021 → Aug 2024 — New York State Psychiatric Institute Suspended No outcome recorded
Phase 2 NCT04576507 Jun 2021 → Dec 2023 — New York State Psychiatric Institute Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT03994640 Jan → Oct 2018 myofascial pain syndrome, temporomandibular joint disorder Medical University of Silesia Completed No outcome recorded
Phase 33 trials
Phase 3 NCT05288010 Mar → Jun 2022 chronic pain syndrome Harley Street (CPC) Limited Unknown No outcome recorded
Phase 3 NCT02955329 Mar → Nov 2019 cannabis dependence University of California, San Francisco Completed No outcome recorded
Phase 3 NCT02892591 Jun 2017 → Jun 2023 spondylosis, cervical University of Colorado, Denver Completed No outcome recorded
Phase not applicable11 trials · 1 missed
— NCT03734731 Jun 2026 → Feb 2027 expected cardiovascular disorder, chronic pain syndrome American Association of Sensory Electrodiagnostic Medicine Not yet recruiting No outcome recorded
— NCT06975020 Dec 2025 → Dec 2026 expected — University of Basel Recruiting No outcome recorded
— NCT07105449 Oct 2025 → Mar 2028 expected thrombocytopenia 3 Centre for Addiction and Mental Health Recruiting No outcome recorded
— NCT07417059 Jun 2025 → Dec 2026 expected cannabis dependence Maastricht University Recruiting No outcome recorded
— NCT05526196 Oct 2024 → Feb 2027 expected — Centre for Addiction and Mental Health Recruiting No outcome recorded
— NCT06595576 Oct 2024 → Apr 2025 — Centre for Addiction and Mental Health Completed No outcome recorded
— NCT04325958 Mar 2024 → Mar 2027 expected — Centre for Addiction and Mental Health Recruiting No outcome recorded
— NCT06435650 Jul → Dec 2023 — London Metropolitan University Completed No outcome recorded
— NCT04827992 Aug 2021 → May 2025 cannabis dependence Massachusetts General Hospital Completed Missed primary
— NCT04230460 Sep 2020 → May 2021 alcohol-induced mental disorder, poisoning Advanced Brain Monitoring, Inc. Completed No outcome recorded
Comparator or background therapy17 trials
Phase 0 NCT03204305 Comparator Sep 2017 → Mar 2020 cannabis dependence Johns Hopkins University Completed No outcome recorded
Phase 1 NCT02177513 Comparator Jun 2014 → Apr 2016 cannabis dependence National Institute on Drug Abuse (NIDA) Completed No outcome recorded
Phase 1 NCT02033707 Background Apr 2014 → Feb 2019 — Johns Hopkins University Completed No outcome recorded
Phase 1 NCT00946348 Comparator Dec 2009 → Oct 2012 cannabis dependence, schizoaffective disorder, schizophrenia Dartmouth-Hitchcock Medical Center Completed No outcome recorded
Phase 1 NCT02675842 Comparator ? → Oct 2021 lung cancer New York State Psychiatric Institute Withdrawn No outcome recorded Stop: Business

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2025-12-19 Ananda Pharma plc Regulatory Ananda Pharma PLC - US Cannabis Rescheduling anandapharma.co.uk ↗
We welcome this decisive move from President Trump to formally recognise the medicinal benefit of cannabis.
2025-12-19 MediPharm Labs Corp Regulatory Historic U.S. Cannabis Rescheduling Unlocks Potential Growth Opportunities for MediPharm Labs Backed by the Company's Suite of Licenses and Proven U.S. Clinical Trial Supply Experience medipharmlabs.com ↗
This change recognizes the medical use of cannabis and reduces barriers to research.
2018-08-23 Quantum Biopharma Results FSD Pharma reports positive pre-clinical results for proprietary CBD combination product issuerdirect.com ↗
FSD Pharma reports positive pre-clinical results for proprietary CBD combination product

All press releases naming this drug 50 releases

DateIssuerRelease

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 114 sources stand behind the page.

FieldValueCited text
Known as cannabis “Hallucinogens: DMT, 4-phosphoryloloxy-N-diethyltryptamine, dipropyltryptamine (DPT), ketamine, dextromethorphan, mescaline, PCP, psilocybin, salvinorin-A, LSD, d-lysergic acid...” NCT02033707 ↗
90

“Active Marijuana: Active Marijuana (active inhaled cannabis) will be administered through a vaporizer once per study session day (Day 1, 7, 14) per block (3 blocks total).” NCT07434895 ↗

“Cannabis induces a clinical response in patients with Crohn's disease: a prospective placebo-controlled study.” PMID 23648372 ↗ May 2013

“Given cannabis gummy PO” NCT07658677 ↗

NCT02710097 ↗

NCT05602649 ↗

NCT04124432 ↗

NCT03247244 ↗

NCT03676166 ↗

NCT01983267 ↗

NCT03656029 ↗

Show 80 more sources

Known as Avidekel “medical cannabis oil "Avidekel" for the reduction of behavioral disturbances among patients with dementia.” PMID 36148467 ↗ Sep 2022
Known as Cannabis sativa “The marijuana plant Cannabis sativa has been reported to produce beneficial effects for patients with inflammatory bowel diseases, but this has not been investigated in...” PMID 23648372 ↗ May 2013
Known as marijuana “This research is being done to measure the effects of both oral and vaporized cannabis (marijuana), at different doses, on the ability to perform certain tasks such as...” NCT03122691 ↗
29

“The purpose of this study is to learn if the use of inhaled cannabis (marijuana) and oral cannabinoid (dronabinol, Marinol or THC, which is an active ingredient of marijuana)...” NCT00260741 ↗

“The purpose of this study is to determine if medicinal cannabis (marijuana) is safe and effective for treating pain in individuals with HIV-associated distal,...” NCT00255580 ↗

“Smoked marijuana (MJ) and dronabinol (also known as THC or by the trade name Marinol) are used to increase appetite, food intake, and weight in patients with HIV who experience...” NCT00079560 ↗

“The marijuana plant Cannabis sativa has been reported to produce beneficial effects for patients with inflammatory bowel diseases, but this has not been investigated in...” PMID 23648372 ↗ May 2013

“Active Marijuana: Active Marijuana (active inhaled cannabis) will be administered through a vaporizer once per study session day (Day 1, 7, 14) per block (3 blocks total).” NCT07434895 ↗

“Cannabis, which some people call marijuana, refers to the dried leaves, flowers, stems, and seeds of the cannabis sativa L plant.” NCT07658677 ↗

“Marijuana (cannabis) is an illegal drug.” NCT02177513 ↗

“marijuana” NCT02892591 ↗

NCT00374127 ↗

NCT03546790 ↗

Show 19 more sources

Known as V-MJ “This study will investigate the ability of vaporized marijuana (V-MJ) (0.00, 12.5, and 25 mg: concentration= 11.7% THC + 0.04% CBD) to reduce the severity of opioid withdrawal...” NCT05114460 ↗
Known as vaporized marijuana “This study will investigate the ability of vaporized marijuana (V-MJ) (0.00, 12.5, and 25 mg: concentration= 11.7% THC + 0.04% CBD) to reduce the severity of opioid withdrawal...” NCT05114460 ↗
Modality Traditional medicine (herbal / TCM) “The marijuana plant Cannabis has been used for centuries in the medicinal treatment of many disorders” NCT01040910 ↗
Route Inhaled “Smoked marijuana (MJ)” NCT00079560 ↗