drugset / Trial / NCT03246113
Tolerability of Cannabis in Patients Receiving Concurrent Chemoradiation for Glioblastoma
NaSingle-groupOpen-labelTreatment
Summary
The goal of this single arm Phase I feasibility study is to investigate the tolerability of cannabis with concurrent chemoradiation in the treatment of glioblastoma multiforme (GBM). A strain of cannabis provided by The National Institute of Drug Abuse (NIDA) that has a high concentration of cannabidiol (CBD) and a low concentration of THC (relative to average street cannabis) will be tested in order to maximize clinical efficacy while minimizing intoxicating side effects in this medically-ill population.
Timeline
- Start
- 2018-03-19
- Primary completion
- 2019-05-09
- Completion
- 2019-05-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cannabis | Traditional medicine (herbal / TCM) | 0.5 unknown | Inhaled |
| Subject | Cannabis | Traditional medicine (herbal / TCM) | 2 unknown | Inhaled |
| Background | Temozolomide | Small molecule | — | Oral |