drugset / Trial / NCT03251326
Nabilone in Cannabis Users With PTSD
Phase 1/2
Terminated
4 enrolled
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA) · collab
RandomizedCrossoverDouble-blindBasic science
Summary
Despite the prevalence of cannabis use among the PTSD population and self-reports that it is used to help cope with PTSD symptoms, the direct effects of cannabis on PTSD symptomology are unknown. The purpose of this placebo-controlled, within-subject study is to assess the effects of smoked cannabis and orally administered nabilone, a synthetic analog of THC, the primary psychoactive component of cannabis on multiple dimensions of PTSD symptomatology in cannabis smokers with PTSD.
Timeline
- Start
- 2015-10
- Primary completion
- 2019-06
- Completion
- 2019-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cannabis | Traditional medicine (herbal / TCM) | 0 % | Inhaled |
| Subject | Cannabis | Traditional medicine (herbal / TCM) | 5.6 % | Inhaled |
| Subject | Nabilone | Other / unclassified | 4 mg | Oral |
| Comparator | Propranolol | Small molecule | 40 mg | — |