drugset / Trial / NCT05999383
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
Phase 2
Recruiting
48 enrolled
University of California, San Francisco
Food and Drug Administration (FDA) · collabNational Institute on Drug Abuse (NIDA) · collabNational Institutes of Health (NIH) · collab
RandomizedCrossoverDouble-blindBasic science
Summary
This is a crossover, randomized, double-blinded clinical pharmacology study enrolling dual cannabis-tobacco smokers to better understand the combined effects of co-administering cannabis and tobacco. The project aims to describe the pharmacokinetics and pharmacodynamics of marijuana-tobacco co-administration by delivering THC and nicotine in various combinations. This foundational study will establish a research program focused on elucidating the public health consequences of marijuana-tobacco co-use.
Timeline
- Start
- 2025-07-01
- Primary completion
- 2028-02-01
- Completion
- 2028-02-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cannabis | Traditional medicine (herbal / TCM) | — | Inhaled |
| Subject | Nicotine | Unknown | — | Inhaled |
Indications
No indication recorded.