drugset / Trial / NCT07661446

Cannabis and Opioid Use Disorder, Study 2

NCT07661446

Phase 1 Not yet recruiting 100 enrolled University of Kentucky
RandomizedCrossoverTriple-blindBasic science

Summary

This inpatient study enrolls healthy individuals who have opioid use disorder. Participants live at the University of Kentucky Hospital for approx. 6 weeks. During this time, we will examine how repeated doses of oral cannabis and acute doses of oral and inhaled cannabis 1) modify the intensity and time course of opioid withdrawal, 2) modify the effects of intranasal opioid administration and 3) impact the safety of opioid administration.

Timeline

Start
2026-07-30
Primary completion
2029-07-30
Completion
2030-01-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Cannabis Traditional medicine (herbal / TCM) Inhaled