drugset / Trial / NCT00403117
Effects of a Range of Naltrexone Doses in Combination With Smoked Marijuana
Phase 2
Completed
49 enrolled
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA) · collabResearch Foundation for Mental Hygiene, Inc. · collab
RandomizedSingle-groupDouble-blindBasic science
Summary
The purpose of this study is to determine if the subjective effects of marijuana will be decreased by low-doses (\< 25 mg) of naltrexone and increased by high-doses (\> 50 mg) of naltrexone.
Timeline
- Start
- 2006-12
- Primary completion
- 2008-05
- Completion
- 2010-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cannabis | Traditional medicine (herbal / TCM) | 3.27 % | Inhaled |
| Subject | Cannabis | Traditional medicine (herbal / TCM) | 800 mg | Inhaled |
| Subject | Naltrexone | Small molecule | 12 mg | — |
| Subject | Naltrexone | Small molecule | 25 mg | — |
| Subject | Naltrexone | Small molecule | 50 mg | — |
| Subject | Naltrexone | Small molecule | 100 mg | — |