drugset
drugset / Trial / NCT05602649

The Impact of Product Formulation on the Pharmacokinetics and Pharmacodynamics of Cannabis Edibles

NCT05602649 ↗

Phase 1 Recruiting 80 enrolled Johns Hopkins University National Institute on Drug Abuse (NIDA) · collab
RandomizedCrossoverDouble-blindBasic science

Summary

This study will examine the pharmacokinetics and pharmacodynamics of delta-9-tetrahydrocannabinol (THC)-infused chocolates, gummies, and drinks. Healthy adults (N=40) will complete 9 drug administration sessions, including an overnight stay prior to each session. Participants will consume THC containing products in a fasted state; following drug administration, the participants will complete cognitive and psychomotor tasks, subjective assessments, have blood collected, and vital signs monitored.

Timeline

Start
2024-07-10
Primary completion
2027-01
Completion
2027-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cannabis Traditional medicine (herbal / TCM) 10 mg Oral
Subject Cannabis Traditional medicine (herbal / TCM) 25 mg Oral

Indications

No indication recorded.