drugset / Trial / NCT00047775
African-American Heart Failure Trial
RandomizedSingle-groupDouble-blindTreatment
Summary
A placebo-controlled trial of BiDil added to standard therapy in African-American patients with heart failure.
Timeline
- Start
- 2001-05
- Primary completion
- —
- Completion
- 2004-08
Publications
- Anand IS, Win S, Rector TS, Cohn JN, Taylor AL. Effect of fixed-dose combination of isosorbide dinitrate and hydralazine on all hospitalizations and on 30-day readmission rates in patients with heart failure: results from the African-American Heart Failure Trial. Circ Heart Fail. 2014 Sep;7(5):759-65. doi: 10.1161/CIRCHEARTFAILURE.114.001360. Epub 2014 Jun 26.
- Mitchell JE, Tam SW, Trivedi K, Taylor AL, O'Neal W, Cohn JN, Worcel M. Atrial fibrillation and mortality in African American patients with heart failure: results from the African American Heart Failure Trial (A-HeFT). Am Heart J. 2011 Jul;162(1):154-9. doi: 10.1016/j.ahj.2011.04.022.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Hydralazine | Small molecule | — | — |
| Subject | Isosorbide Dinitrate | Other / unclassified | — | — |