drugset
drugset / Trial / NCT00053118

Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer

NCT00053118 ↗

Phase 1 Completed 1 enrolled Roswell Park Cancer Institute
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining chemotherapy with peripheral stem cell transplantation in treating children who have central nervous system cancer.

Timeline

Start
2002-03
Primary completion
2004-07
Completion
2004-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule — Intravenous
Background Etoposide Small molecule — Intravenous
Background filgrastim Protein / enzyme biologic — Intravenous

Indications

central nervous system cancer lymphoma neuroblastoma retinoblastoma