drugset / Trial / NCT00054548

Combination Chemotherapy Plus Oblimersen in Treating Patients With Advanced Solid Tumors

NCT00054548

Phase 1 Completed 55 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Phase I trial to study the effectiveness of combining carboplatin and paclitaxel with oblimersen in treating patients who have advanced solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Oblimersen may increase the effectiveness of carboplatin and paclitaxel by making tumor cells more sensitive to the drugs.

Timeline

Start
2002-10
Primary completion
2008-05
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Paclitaxel Small molecule Intravenous
Subject oblimersen sodium Antisense oligonucleotide Intravenous