drugset / Trial / NCT00054548
Combination Chemotherapy Plus Oblimersen in Treating Patients With Advanced Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
Phase I trial to study the effectiveness of combining carboplatin and paclitaxel with oblimersen in treating patients who have advanced solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Oblimersen may increase the effectiveness of carboplatin and paclitaxel by making tumor cells more sensitive to the drugs.
Timeline
- Start
- 2002-10
- Primary completion
- 2008-05
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Paclitaxel | Small molecule | — | Intravenous |
| Subject | oblimersen sodium | Antisense oligonucleotide | — | Intravenous |