drugset / Trial / NCT00070733

The Effect of 5-Alpha Reductase on Testosterone in Men

NCT00070733

RandomizedParallel-groupDouble-blindTreatment

Summary

The enzyme 5-alpha reductase is present in small amounts in muscle and converts testosterone to dihydrotestosterone (DHT). Testosterone affects lean body tissue, muscle size, muscle strength, and sexual function in men. This study will evaluate how 5-alpha reductase influences the effects of testosterone in young healthy men.

Timeline

Start
2003-08
Primary completion
Completion
2005-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Dutasteride Small molecule
Subject Testosterone Enanthate Small molecule

Indications