drugset / Trial / NCT00079092
Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma
Phase 2
Completed
18 enrolled
Wake Forest University Health Sciences
National Cancer Institute (NCI) · collab
Open-labelTreatment
Summary
RATIONALE: Thalidomide may stop the growth of malignant glioma by stopping blood flow to the tumor. Drugs used in chemotherapy, such as procarbazine, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining thalidomide with procarbazine may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving thalidomide together with procarbazine works in treating patients with recurrent or progressive malignant glioma.
Timeline
- Start
- 2004-01-01
- Primary completion
- 2006-03-21
- Completion
- 2006-03-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Thalidomide | Other / unclassified | — | Oral |
| Subject | procarbazine | Small molecule | — | Oral |