drugset / Trial / NCT00079352

Flavopiridol, Gemcitabine, and Irinotecan in Treating Patients With Unresectable or Metastatic Solid Tumors

NCT00079352

Phase 1 Completed 24 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial is studying the side effects and best dose of flavopiridol when given together with gemcitabine and irinotecan in treating patients with unresectable or metastatic solid tumors. Drugs used in chemotherapy, such as flavopiridol, gemcitabine, and irinotecan, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells

Timeline

Start
2004-04
Primary completion
2007-10
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject alvocidib Small molecule Intravenous
Background Gemcitabine Small molecule Intravenous
Background Irinotecan Small molecule Intravenous