drugset / Trial / NCT00090493

Study of MAGE-A3 and NY-ESO-1 Immunotherapy in Combo With DTPACE Chemo and Auto Transplantation in Multiple Myeloma

NCT00090493

Phase 2/3 Completed 4 enrolled University of Arkansas
NaSingle-groupOpen-labelTreatment

Summary

The hope is that the peptide vaccines will stimulate the immune system to attack and kill the myeloma cells. The purpose is to generate anti-myeloma T-cells which will kill myeloma cells and nothing else.

Timeline

Start
2004-06
Primary completion
2007-07
Completion
2012-05

Drugs

EvaluationDrugModalityDoseRoute
Subject MAGE-A3 Vaccine 300 ug Subcutaneous
Subject NY-ESO-1 Protein / enzyme biologic 300 ug Subcutaneous
Background sargramostim Protein / enzyme biologic 250 ug Subcutaneous
Background sargramostim Protein / enzyme biologic 500 ug Subcutaneous

Indications