drugset / Trial / NCT00096473

Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease

NCT00096473

Phase 3 Completed 229 enrolled Eisai Inc. Pfizer · collab
RandomizedParallel-groupDouble-blindTreatment

Summary

Donepezil hydrochloride (Aricept) has been approved to treat symptoms associated with mild to moderate Alzheimer's disease (AD). Aricept has been shown to improve the memory and thinking abilities, activities of daily living and global function in patients. The purpose of the study is to further investigate the effectiveness and safety of donepezil in patients with severe Alzheimer's disease. Donepezil is thought to work in the brain by increasing the levels of an important brain chemical called acetylcholine. This chemical helps a person's memory to work better.

Timeline

Start
2001-01
Primary completion
2005-06
Completion
2005-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Donepezil Small molecule

Indications