drugset / Trial / NCT00106340

Vildagliptin Compared to Glimepiride in Combination With Metformin in Patients With Type 2 Diabetes

NCT00106340

Phase 3 Completed 3118 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Many people with type 2 diabetes cannot maintain target blood glucose levels when taking a single oral drug. The purpose of this study is to assess the long term safety and effectiveness of vildagliptin, an unapproved drug, compared to that of glimepiride in lowering overall blood glucose levels when added to metformin in people with type 2 diabetes not at target blood glucose levels on metformin alone.

Timeline

Start
2005-03
Primary completion
2008-05
Completion
2008-05-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Glimepiride Small molecule
Subject Vildagliptin Other / unclassified
Background Metformin Small molecule