drugset / Trial / NCT00107874

Oral Misoprostol Versus Intravenous Oxytocin in Preventing Blood Loss After Non-scheduled Cesarean Section

NCT00107874

Phase 2 Completed 56 enrolled University Hospital, Basel, Switzerland
RandomizedParallel-groupDouble-blindPrevention

Summary

Postpartum hemorrhage (PPH) ranks among the leading causes of maternal morbidity and mortality, both in developed and developing countries. With this trial, we sought to determine the effectiveness of oral misoprostol as an uterotonic drug in comparison with intravenous oxytocin, in patients with a low risk of PPH undergoing non-scheduled Cesarean section. We therefore compared the intra- and postoperative blood loss, as well as drug related side effects in patients, treated by the same surgical and anesthesiological team in one institution.

Timeline

Start
1999-01
Primary completion
2002-02
Completion
2002-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Misoprostol Other / unclassified Oral

Indications

No indication recorded.