Drugs / Misoprostol
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Misoprostol

Other / unclassified

Developed for
cervix disorder · pregnancy disorder · pregnancy disorder with abortive outcome · leiomyoma · uterine disorder · menstrual disorder · endometrial disorder · habitual spontaneous abortion
+37 more · indomethacin embryofetopathy · pregnancy loss, recurrent, 4 · Clostridium difficile colitis · constipation disorder · dystocia · endometrial polyp · erectile dysfunction · gas bloat syndrome · hemorrhagic disease · hypertension, pregnancy-induced · morbid obesity · newborn respiratory distress syndrome · obstetric disorder · perinatal disease · persistent tachypnoe of infancy, usual · preeclampsia · preterm premature rupture of the membranes · submucous uterine fibroid · thrombotic disease · uterine inflammatory disease · active peptic ulcer disease · cervical dystonia · female reproductive system disorder · fetal growth restriction · gastric ulcer · gastroduodenitis · gestational diabetes · metabolic dysfunction-associated steatohepatitis · oligohydramnios · pain agnosia · placenta disorder · placenta praevia · pulmonary hypertension · respiratory failure · severe pre-eclampsia · ulcer disease · uterine corpus leiomyoma
Investigated by
Gynuity Health Projects · Ain Shams University · Assiut University · Cairo University · Ferring Pharmaceuticals · Aswan University Hospital
+184 more · Family Care International · University of California, San Francisco · University of Pittsburgh · Aga Khan Health Services · China Medical University Hospital · Department of Medical Services Ministry of Public Health of Thailand · Hormozgan University of Medical Sciences · Ibis Reproductive Health · Jawaharlal Nehru Medical College · The Aga Khan Foundation · University of Liverpool · University of Pennsylvania · Aga Khan University · Assistance Publique - Hôpitaux de Paris · Assistance Publique Hopitaux De Marseille · Assuta Ashdod Hospital · Bill and Melinda Gates Foundation · Boston University · HaEmek Medical Center, Israel · Islamabad Medical and Dental College · Karolinska Institutet · Mahidol University · Mbarara University of Science and Technology · Montefiore Medical Center · Northwestern University · Planned Parenthood League of Massachusetts · Society of Family Planning · Stony Brook University · University of Arizona · University of Utah · hany farouk · American University of Beirut Medical Center · Antonios Likourezos · Assuta Medical Center · AstraZeneca · Aultman Health Foundation · Bangkok Metropolitan Administration Medical College and Vajira Hospital · Beni-Suef University · Bezmialem Vakif University · Bharatpur Eye Hospital · Brigham and Women's Hospital · CHA University · CREHPA · Cameroon Baptist Convention Health · Canadian Anesthesiologists' Society · Center for Research on Environment, Health and Population Activities · Centre de Formation et de la Recherche, Tunisia · Centro Rosarino de Estudios Perinatales · Charitable Foundation Women Health & Family Planning · ChildFund International · Cipla Ltd. · Clinical Hospital Merkur · Columbia University · Consorci Sanitari de Terrassa · Daga Memorial Women's Hospital, Nagpur, India · David Young · Department of Health and Family Welfare, Government of Gujarat · Department of Medical Research, Lower Myanmar · Dr Mudassar Saeed Pansota · Dr. Sami Ulus Children's Hospital · Effective Care Research Unit · El Galaa Teaching Hospital · Emory University · Faculty of Medicine of Tunis · Fogarty International Center of the National Institute of Health · Global Network for Women's and Children's Health Research · Government Medical College, Nagpur · Guttmacher Institute · HAWLER Maternity Hospital · Hagar Muhammad Abdulfattah Muhammad · Hamna Khaliq · Hawler Medical University · Hayat Abad Medical Complex, Peshawar · Henry Aristoteles Mate-Sánez · all 190 on the full record

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved US (FDA) CYTOTEC 1988-12-27 fda.gov

Trials 224 · started per year

today
US approved 1988
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19881989199019911992199319941995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 05 trials
Phase 0 NCT06874049 Feb → Aug 2025 overdue Hagar Muhammad Abdulfattah Muhammad Active not recruiting No outcome recorded
Phase 0 NCT06199154 Jul 2024 → May 2026 overdue morbid obesity, pregnancy disorder University of Maryland, Baltimore Recruiting No outcome recorded
Phase 0 NCT04768010 Aug → Sep 2023 constipation disorder, gas bloat syndrome Montefiore Medical Center Withdrawn No outcome recorded
Phase 0 NCT02424201 Jun → Dec 2015 pregnancy disorder Lagos State University Unknown No outcome recorded
Phase 0 NCT02259309 Nov 2014 → Jul 2015 Vanderbilt University Completed No outcome recorded
Phase 17 trials
Phase 1 NCT07526064 May → Jul 2026 overdue pregnancy disorder with abortive outcome Hamna Khaliq Not yet recruiting No outcome recorded
Phase 1 NCT06502158 Oct 2024 → Oct 2026 expected Montefiore Medical Center Recruiting No outcome recorded
Phase 1 NCT06364098 Jan 2022 → Feb 2023 Cairo University Completed No outcome recorded
Phase 1 NCT01863706 May → Dec 2013 Hormozgan University of Medical Sciences Completed No outcome recorded
Phase 1 NCT01271257 Jan 2011 → Dec 2014 China Medical University Hospital Completed No outcome recorded
Phase 1 NCT00592215 Mar 2008 → Apr 2010 Johns Hopkins University Withdrawn No outcome recorded
Phase 1 NCT00906126 Apr 2007 → Sep 2008 dystocia University of Texas Southwestern Medical Center Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT00432588 preeclampsia, preterm premature rupture of the membranes Hormozgan University of Medical Sciences Unknown No outcome recorded
Phase 226 trials
Phase 2 NCT06452719 Aug 2024 → Jul 2026 overdue pregnancy disorder with abortive outcome, pregnancy loss, recurrent, 4 University of Pennsylvania Recruiting No outcome recorded
Phase 2 NCT05216952 May 2022 → Jan 2023 pregnancy disorder with abortive outcome University of North Carolina, Chapel Hill Completed No outcome recorded
Phase 2 NCT05207644 Dec 2021 → Apr 2022 pregnancy disorder Gynuity Health Projects Completed No outcome recorded
Phase 2 NCT04724187 Feb → Aug 2021 Islamabad Medical and Dental College Unknown No outcome recorded
Phase 2 NCT04604366 Nov 2020 → Dec 2021 pregnancy disorder with abortive outcome Islamabad Medical and Dental College Completed No outcome recorded
Phase 2 NCT03972358 Feb 2020 → Dec 2021 menstrual disorder Gynuity Health Projects Unknown No outcome recorded
Phase 2 NCT03927807 Mar → Dec 2019 Ain Shams University Unknown No outcome recorded
Phase 2 NCT03617172 Nov 2018 → Sep 2021 Clostridium difficile colitis Vanderbilt University Medical Center Terminated No outcome recorded
Phase 2 NCT03939663 Jul 2018 → Jul 2019 Ain Shams University Unknown No outcome recorded
Phase 2 NCT02685085 Feb → Aug 2016 Woman's Health University Hospital, Egypt Unknown No outcome recorded
Phase 2/311 trials
Phase 2/3 NCT07576881 Jun 2026 → Dec 2027 expected pregnancy disorder Indiana University Not yet recruiting No outcome recorded
Phase 2/3 NCT05957666 Jun → Dec 2023 Services Institute of Medical Sciences, Pakistan Unknown No outcome recorded
Phase 2/3 NCT04270994 Sep 2016 → Aug 2019 endometrial polyp Henry Aristoteles Mate-Sánez Completed No outcome recorded
Phase 2/3 NCT02901561 Sep → Dec 2016 Assiut University Completed No outcome recorded
Phase 2/3 NCT02509351 Oct 2015 → Nov 2016 Ain Shams University Completed No outcome recorded
Phase 2/3 NCT02299401 Dec 2014 → Oct 2016 pregnancy disorder Gynuity Health Projects Completed No outcome recorded
Phase 2/3 NCT02141321 May 2014 → Jan 2015 Ain Shams University Completed No outcome recorded
Phase 2/3 NCT02083107 Feb 2013 → Feb 2014 Ain Shams University Completed No outcome recorded
Phase 2/3 NCT01477840 Aug 2012 Soudabeh Eshghi ali Unknown No outcome recorded
Phase 2/3 NCT01615224 May 2012 → Oct 2019 pregnancy disorder with abortive outcome Kristina Gemzell Danielsson Terminated No outcome recorded
Phase 339 trials
Phase 3 NCT07506512 Jul 2026 → Jul 2031 expected pregnancy loss, recurrent, 4 University of Pennsylvania Not yet recruiting No outcome recorded
Phase 3 NCT05245227 Jan 2025 → Jan 2027 expected Stony Brook University Recruiting No outcome recorded
Phase 3 NCT06078501 Feb → Jul 2024 Stanford University Terminated No outcome recorded
Phase 3 NCT05839899 Aug 2023 → Jul 2024 Planned Parenthood League of Massachusetts Unknown No outcome recorded
Phase 3 NCT05424445 Jan → Dec 2022 Karolinska Institutet Completed No outcome recorded
Phase 3 NCT04635007 Jan 2021 → Jun 2022 Cairo University Completed No outcome recorded
Phase 3 NCT04560218 Oct 2020 → Jul 2021 Department of Medical Services Ministry of Public Health of Thailand Completed No outcome recorded
Phase 3 NCT04339348 Apr 2020 → Feb 2021 Cairo University Completed No outcome recorded
Phase 3 NCT04152317 Nov 2019 → Sep 2020 cervix disorder Professor Fernando Figueira Integral Medicine Institute Completed No outcome recorded
Phase 3 NCT05108597 Mar 2019 → Mar 2020 leiomyoma Pak Emirates Military Hospital Completed No outcome recorded
Phase 456 trials
Phase 4 NCT07671989 Jun → Dec 2026 expected menstrual disorder University of California, San Francisco Recruiting No outcome recorded
Phase 4 NCT07286188 Dec 2025 → Dec 2026 expected leiomyoma Northwestern University Recruiting No outcome recorded
Phase 4 NCT07604051 Nov 2025 → Apr 2026 Dr Mudassar Saeed Pansota Completed No outcome recorded
Phase 4 NCT07174856 Oct 2025 → Jan 2027 expected Ibis Reproductive Health Not yet recruiting No outcome recorded
Phase 4 NCT06049745 Nov 2023 → Aug 2026 overdue submucous uterine fibroid Assuta Ashdod Hospital Not yet recruiting No outcome recorded
Phase 4 NCT05119439 Oct 2022 → Jun 2023 Gynuity Health Projects Terminated No outcome recorded
Phase 4 NCT05262738 Jun 2022 → Jul 2023 obesity disorder, pregnancy disorder University of Texas at Austin Completed No outcome recorded
Phase 4 NCT05124314 Oct 2021 → Oct 2023 Clinical Hospital Merkur Unknown No outcome recorded
Phase 4 NCT04940013 Oct 2021 → Sep 2025 menstrual disorder University of California, San Francisco Terminated No outcome recorded
Phase 4 NCT05046041 Nov 2020 → Aug 2021 Gynuity Health Projects Completed No outcome recorded
Phase not applicable79 trials
NCT07697781 Jan → Jul 2026 overdue endometrial disorder Faculty of Medicine of Tunis Recruiting No outcome recorded
NCT07559812 Oct 2025 → Apr 2026 overdue cervix disorder, pregnancy disorder Mayo Hospital Lahore Active not recruiting No outcome recorded
NCT06669533 Feb 2025 → Nov 2026 expected cervical cancer University of Alabama at Birmingham Recruiting No outcome recorded
NCT06850974 Feb 2025 → Mar 2027 expected Stony Brook University Recruiting No outcome recorded
NCT07416487 Feb → Dec 2025 Muhammad Aamir Latif Completed No outcome recorded
NCT07534982 Jul 2024 → Jul 2027 expected Yael Yagur Recruiting No outcome recorded
NCT07121634 Jan 2024 → Aug 2025 overdue cervix disorder Raid M. Al-Ani Active not recruiting No outcome recorded
NCT06060327 Oct 2023 → Jun 2024 Cairo University Completed No outcome recorded
NCT05532215 Mar → Oct 2023 OZORI EBIOGBO STANLEY Unknown No outcome recorded
NCT05696574 Jan → Jun 2023 pregnancy disorder Cairo University Unknown No outcome recorded
Also used as a comparator or background therapy in 234 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 08 trials
Phase 0 NCT07109258 Comparator May → Sep 2025 overdue Cairo University Recruiting No outcome recorded
Phase 0 NCT06207539 Background Dec 2022 → Mar 2023 Ain Shams Maternity Hospital Completed No outcome recorded
Phase 0 NCT05342974 Background Apr 2022 → Dec 2023 University of Utah Completed No outcome recorded
Phase 0 NCT05001061 Comparator Aug → Oct 2021 pregnancy disorder with abortive outcome Cairo University Unknown No outcome recorded
Phase 0 NCT04478942 Comparator Oct 2020 → Jan 2025 preterm premature rupture of the membranes University of Wisconsin, Madison Completed No outcome recorded
Phase 16 trials
Phase 1 NCT04981457 Comparator Mar → Sep 2021 pregnancy disorder with abortive outcome Cairo University Unknown No outcome recorded
Phase 1 NCT03390010 Comparator Dec 2017 → Feb 2018 Aljazeera Hospital Completed No outcome recorded
Phase 1 NCT02412033 Comparator Mar → Apr 2016 Assiut University Completed No outcome recorded
Phase 1 NCT02516631 Comparator Nov 2014 → Nov 2015 Region Skane Completed No outcome recorded
Phase 1 NCT01840813 Comparator Apr 2011 → Mar 2012 placenta disorder Hawler Medical University Completed No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT05306405 Comparator Feb → Aug 2022 cervix disorder Ain Shams University Unknown No outcome recorded
Phase 1/2 NCT03523754 Background Jan → Oct 2018 Dina Yahia Mansour Unknown No outcome recorded
Phase 1/2 NCT01571323 Comparator Feb → Aug 2012 Qazvin University Of Medical Sciences Completed No outcome recorded
Phase 223 trials
Phase 2 NCT05804305 Comparator Jul → Dec 2022 metabolic dysfunction-associated steatohepatitis Ziauddin University Completed No outcome recorded
Phase 2 NCT04533841 Comparator Feb → Sep 2020 Ahmed mohamed fathy ismail Completed No outcome recorded
Phase 2 NCT04117243 Comparator Jan → Dec 2020 Cairo University Completed No outcome recorded
Phase 2 NCT03854383 Comparator Mar → May 2019 Abdelrahman Ali Fadel Youssef Mohamed Unknown No outcome recorded
Phase 2 NCT03723031 Comparator Nov 2018 → Apr 2020 pregnancy disorder Cairo University Unknown No outcome recorded
Phase 2/314 trials
Phase 2/3 NCT03487354 Comparator Apr 2018 → Jan 2019 pregnancy disorder with abortive outcome Ain Shams University Completed No outcome recorded
Phase 2/3 NCT03479879 Background Mar → Dec 2018 pregnancy disorder with abortive outcome Ain Shams University Completed No outcome recorded
Phase 2/3 NCT03509168 Comparator Jan → May 2018 leiomyoma Makerere University Unknown No outcome recorded
Phase 2/3 NCT03366259 Comparator Dec 2017 → Feb 2018 uterine disorder Kasr El Aini Hospital Unknown No outcome recorded
Phase 2/3 NCT03148717 Comparator May 2017 → Mar 2018 Ain Shams University Completed No outcome recorded
Phase 336 trials
Phase 3 NCT06765473 Comparator Jan 2025 → Jan 2026 overdue Assiut University Not yet recruiting No outcome recorded
Phase 3 NCT06259097 Comparator Jul 2024 → Jul 2026 overdue pregnancy disorder Icahn School of Medicine at Mount Sinai Enrolling by invitation No outcome recorded
Phase 3 NCT06325501 Comparator Mar → Dec 2024 leiomyoma Cairo University Unknown No outcome recorded
Phase 3 NCT05097326 Comparator Jun 2022 → Apr 2023 Stanford University Completed No outcome recorded
Phase 3 NCT04949633 Comparator Sep 2021 → Sep 2026 expected cervix disorder University Hospital, Tours Recruiting No outcome recorded
Phase 470 trials
Phase 4 NCT07690007 Comparator Jun → Dec 2026 expected Peking University First Hospital Not yet recruiting No outcome recorded
Phase 4 NCT07503184 Background Jul 2025 → Jan 2026 preterm premature rupture of the membranes Nishtar Medical University Completed No outcome recorded
Phase 4 NCT07160855 Background May → Nov 2025 overdue Nishtar Medical University Recruiting No outcome recorded
Phase 4 NCT07712510 Comparator Mar → Aug 2025 Medicare Hospital (Pvt) Limited Completed No outcome recorded
Phase 4 NCT06794385 Comparator Jan → Sep 2025 overdue University Medical Centre Ljubljana Not yet recruiting No outcome recorded
Phase not applicable74 trials
NCT07685756 Comparator May → Dec 2026 expected cervix disorder HUDDA Ahmad Active not recruiting No outcome recorded
NCT07353281 Comparator Jan 2026 → Jan 2028 expected puerperal disorder Western Galilee Hospital-Nahariya Not yet recruiting No outcome recorded
NCT07636317 Comparator Jun 2025 → Mar 2026 pregnancy disorder with abortive outcome Sohag University Completed No outcome recorded
NCT07646275 Comparator Apr 2025 → Jan 2026 habitual spontaneous abortion, pregnancy disorder with abortive outcome, pregnancy loss, recurrent, 4 Harran University Completed No outcome recorded
NCT07271056 Comparator Feb → Jul 2025 Benha University Completed No outcome recorded

Evidence & citations 21 cited values

Every value below carries the sentence it was read from. 463 sources stand behind the page.

FieldValueCited text
Known as Misoprostol “In Misoprostol group (n=111), 400 microgram misoprostol (2 tablets - Cytotec, Pfizer, G.D. Searle LLC) will be inserted intraoperative inside the uterus after delivery of the placenta” NCT06060327
444

“OBJECTIVE: To compare the efficacy and safety of a 200-microgram misoprostol vaginal insert with a 10-mg dinoprostone vaginal insert for reducing the time to vaginal delivery.” PMID 23857539 Aug 2013

Misoprostol, a prostaglandin E1 analogue, is the most interesting alternative to Dinoprostone because of its effectiveness, low cost, and temperature stability.” NCT02036437

“A tablet of DA9601, Cytotec (200ug of Misoprostol), Acrofen (100mg of Aceclofenac) will be assigned randomly to the subjects for four weeks.” NCT01912066

“800 micrograms misoprostol vaginally followed by 400 micrograms oral misoprostol every 3 hours with a maximum of four oral doses.” PMID 24084539 Oct 2013

misoprostol tablet (400 mg) was placed into uterine cavity at the fundus after delivery of the placenta and swabbing the cavity” NCT05083910

“Recent evidence however has shown that misoprostol is associated with better outcomes and merits evaluation in our environment.” NCT06343480

“Letrozole 2.5 mg each 12 hours for 2 days followed by vaginal misoprostol 800 mcg for induction of abortion” NCT04590482

“the recommended use of mifepristone or misoprostol as cervical preparation for the abortions after 12 weeks” NCT01795599

“The first regimen will include a 200 mg oral dose of mifepristone followed by 800 mcg buccal misoprostol.” NCT01387256

“Dose reservoir of 100 mcg of misoprostol in a hydrogel polymer vaginal insert within a retrieval system.” NCT00828711

“Dose reservoir of 200 mcg of misoprostol in a hydrogel polymer vaginal insert within a retrieval system.” NCT01283022

“received a single sublingual dose of 400 mcg misoprostol or placebo 3 h prior to the LNG-IUS insertion.” PMID 20472114 Mar 2010

“slow-release vaginal dinoprostone; oral misoprostol 25 µg; dinoprostone vaginal gel 2 mg” PMID 37068892 Apr 2023

“Administration of oral Mifepristone 600 mg and oral Misoprostol 400 mcg concomitantly.” NCT03440866

“800 μg buccal misoprostol through 70 days LMP following administration of mifepristone” NCT02985229

“only vaginal misoprostol 25 μg tablets will be applied for induction of laour” NCT05306405

Misoprostol 800 mcg buccally on day 2 (24 hours after mifepristone).” NCT03972358

“200 mg oral Mifepristone simultaneously 400 mcg buccal misoprostolNCT01768299

“NSAIDs: ibuprofen, celecoxib, or diclofenac/misoprostolNCT01943435

Misoprostol is a synthetic prostaglandin E1 analogue.” NCT02516631

Misoprostol 25 mcg inserted for one or multiple doses” NCT06151925

“Rectal diclofenac 100mg and misoprostol 400mcg stat” NCT03518463

Misoprostol, Dinoprostone, amniotomy, Oxytocin” NCT00385229

misoprostol 600 mcg will be given buccally” NCT01549223

“Mifépristone versus MisoprostolNCT03043014

“600 mcg misoprostol oral” NCT01487278

“intravaginal misoprostolNCT02574338

Misoprostol 25Mcg” NCT03523754

misoprostolNCT04751500

NCT04533841

NCT07353281

NCT00116350

NCT04358965

NCT01620814

NCT03710304

NCT05097326

NCT03390010

NCT02639429

NCT02786992

NCT00330993

NCT02679092

NCT01636063

NCT00594854

NCT03796416

NCT02012491

NCT00468299

NCT05568745

NCT01539408

NCT03400683

NCT06452719

NCT03670836

NCT03388827

NCT00140114

NCT00129506

NCT00401440

NCT06325501

NCT01477840

NCT04724187

NCT00670761

NCT03866772

NCT06726278

NCT03829592

NCT04117243

NCT06669533

NCT02707653

NCT02762942

NCT04932382

NCT02902653

NCT04694677

NCT03708497

NCT03106389

NCT02424201

NCT06249815

NCT02704780

NCT01710566

NCT06909721

NCT00576706

NCT03212352

NCT02328495

NCT03144401

NCT00997347

NCT04768010

NCT02053922

NCT01597726

NCT07559812

NCT01931410

NCT04028765

NCT05262738

NCT01615731

NCT02314754

NCT00514618

NCT02539199

NCT01678703

NCT05088707

NCT07121634

NCT02488642

NCT04604366

NCT04891679

NCT06259097

NCT05088720

NCT02086994

NCT03600064

NCT03254628

NCT03366259

NCT04270994

NCT04492072

NCT03927807

NCT00528255

NCT02226588

NCT01571323

NCT04505943

NCT00495560

NCT03479879

NCT03556852

NCT05664659

NCT04505917

NCT02509351

NCT07690007

NCT01939457

NCT02745093

NCT00482209

NCT05147857

NCT00466999

NCT03710317

NCT02318225

NCT02716142

NCT03039036

NCT06056141

NCT01866488

NCT02685085

NCT01231126

NCT03435458

NCT07160855

NCT02981030

NCT05108597

NCT05077540

NCT01866241

NCT03854383

NCT02918110

NCT06946914

NCT04044287

NCT04989400

NCT05001061

NCT03774524

NCT03509168

NCT05119439

NCT04063904

NCT03680339

NCT00299754

NCT00141895

NCT00602095

NCT03829696

NCT00945997

NCT05245227

NCT01519765

NCT01689311

NCT03239327

NCT07506512

NCT04756661

NCT04044079

NCT05207644

NCT02398838

NCT00308711

NCT02908295

NCT00892229

NCT02952807

NCT04560218

NCT03148314

NCT00957346

NCT04339348

NCT07526064

NCT02202967

NCT01506388

NCT02408315

NCT00671060

NCT04514770

NCT05216952

NCT05804305

NCT01754649

NCT02265562

NCT02573051

NCT05928871

NCT02411916

NCT03815344

NCT03490617

NCT00393731

NCT04496908

NCT01510574

NCT02141555

NCT02405156

NCT02168881

NCT01024270

NCT03407521

NCT03584698

NCT04595812

NCT07271056

NCT00120042

NCT00148473

NCT07636317

NCT03863392

NCT07465016

NCT01156688

NCT01307111

NCT03463070

NCT01113229

NCT01139801

NCT05046041

NCT06765473

NCT03930069

NCT02277041

NCT01475318

NCT00120237

NCT00592215

NCT02316301

NCT02901561

NCT03148561

NCT00886860

NCT00886834

NCT00177372

NCT03676621

NCT01508429

NCT03489928

NCT01406392

NCT01173003

NCT02141321

NCT01856985

NCT04635007

NCT03148574

NCT02522130

NCT02522078

NCT04152317

NCT02061657

NCT07697781

NCT04217265

NCT01998776

NCT03870503

NCT00797693

NCT01134926

NCT02412033

NCT02314728

NCT04301349

NCT01840813

NCT04887493

NCT00374621

NCT06207539

NCT05957666

NCT02989324

NCT02534883

NCT03064568

NCT01916681

NCT02279914

NCT01271257

NCT02680314

NCT02277067

NCT06078501

NCT01801410

NCT06502158

NCT04478942

NCT00383942

NCT03748147

NCT06199154

NCT00695331

NCT00969982

NCT02633761

NCT00992524

NCT03044093

NCT05198050

NCT02805426

NCT02720991

NCT01713153

NCT02686840

NCT01933360

NCT03682718

NCT00325026

NCT01612065

NCT03939663

NCT03483142

NCT03870256

NCT05322252

NCT00097123

NCT03744364

NCT01818414

NCT00426491

NCT01147497

NCT05532215

NCT02083107

NCT01733329

NCT00386282

NCT02777190

NCT03148717

NCT04685694

NCT03346629

NCT02401425

NCT03487354

NCT01863706

NCT02732522

NCT03628625

NCT00680394

NCT01615224

NCT05103098

NCT04339049

NCT03269279

NCT03723031

NCT02259309

NCT00269568

NCT01718314

NCT00835731

NCT05674487

NCT02709564

NCT05839899

NCT02738177

NCT01156948

NCT04981457

NCT05862428

NCT00386867

NCT03591913

NCT03976037

NCT00870272

NCT00346840

NCT02485821

NCT01508143

NCT02154932

NCT01862991

NCT02409407

NCT07712510

NCT02209545

NCT05761418

NCT00190294

NCT02758340

NCT04215835

NCT01116050

NCT06049745

NCT00286208

NCT04482881

NCT02480543

NCT01765881

NCT06364098

NCT07685756

NCT07646275

NCT03638856

NCT00784186

NCT02957305

NCT00355303

NCT00572819

NCT02412618

NCT03749902

NCT00925938

NCT05424445

NCT00953641

NCT01199159

NCT01700478

NCT05079061

NCT07534982

NCT02983591

NCT03587077

NCT01070472

NCT00432588

NCT01422226

NCT00363389

NCT00906347

NCT02342002

NCT03134183

NCT02048098

NCT03043014

NCT03777696

NCT04940013

NCT07416487

NCT03928600

NCT01634854

NCT03547778

NCT01466530

NCT05806307

NCT01412073

NCT06009679

NCT03790371

NCT03081442

NCT02474433

NCT03031353

NCT00355966

NCT02562300

NCT01485562

NCT01080846

NCT02515604

NCT00864799

NCT01762319

NCT07671989

NCT01805115

NCT04143685

NCT00677755

NCT02299401

NCT05696574

NCT03140384

NCT02853552

NCT00529295

NCT05857059

NCT03140033

NCT01001897

NCT02985086

NCT01751087

NCT00310921

NCT00324519

NCT03359655

NCT05094375

NCT00200226

NCT06794385

NCT01798017

NCT06874049

NCT00116480

NCT00107874

NCT03675802

NCT05215873

NCT07174856

NCT07576881

NCT01373359

NCT07286188

NCT03774706

NCT04780412

NCT02708446

NCT03617172

NCT06850974

NCT04499976

NCT00613366

NCT02704481

NCT06049160

NCT02546193

NCT05124314

NCT03675672

NCT00906126

NCT02643186

NCT00124540

NCT01436266

NCT01033903

NCT01428037

NCT04080336

NCT07109258

NCT04500002

NCT00674232

NCT01462422

NCT01140971

NCT04273984

NCT04080349

NCT05340205

NCT02163616

NCT05342974

Known as Angusta “A Comparative, Open-label, Parallel Design, Bioavailability Study of Two Misoprostol Formulations (Angusta™ 25 µg Dispersible Tablets vs. Cytotec® 200 µg Tablets) Following...” NCT02516631
2

“Oral misoprostol (ANGUSTA®) 25 µg every 2 hours, 8 times (maximum dosage should not exceed 200µg).” NCT04949633

“Norgine (who make Angusta, a 25 µg oral misoprostol tablet).” PMID 34155622 Jun 2021

Known as Cytotec “A Comparative, Open-label, Parallel Design, Bioavailability Study of Two Misoprostol Formulations (Angusta™ 25 µg Dispersible Tablets vs. Cytotec® 200 µg Tablets) Following...” NCT02516631
17

“In Misoprostol group (n=111), 400 microgram misoprostol (2 tablets - Cytotec, Pfizer, G.D. Searle LLC) will be inserted intraoperative inside the uterus after delivery of the placenta” NCT06060327

“Patients assigned to PO Misoprostol (Cytotec) 400 mg once, 2-4 hours prior to hysteroscopy” NCT02474433

“misoprostol (Cytotec tables; Searle,A Division of Monsanto.P.L.C, England )0.8mg orally” NCT00677755

“only vaginal Misoprostol 800mcg (4 tablets Cytotec 200mcg ) ) every 3 hours” NCT04981457

“Misoprostol (Cytotec) is used widely in Obstetrics and Gynecology” NCT06009679

“800 µg sublingual misoprostol (Cytotec Pfizer, New York, USA)” NCT05077540

“Misoprostol (Cytotec; GD Searle and Co., Chicago, IL)” NCT00426491

“Misoprostol ( Cytotec) 200 microgram a tablet” NCT07465016

“Misoprostol ( Cytotec) 200 microgram a tablet” NCT00797693

“Misoprostol ( Cytotec) 200 microgram a tablet” NCT07697781

“Misoprostol (Cytotec®)” NCT00140114

“Misoprostol (cytotec)” NCT02480543

NCT00256009

NCT02581761

NCT00920465

NCT02013960

NCT01912066

Known as Cytotec (brand name) Cytotec (brand name)NCT04768010
Known as IPGE1 “The objective of this study was to evaluate the feasibility of a randomized controlled trial (RCT) of inhaled PGE1 (IPGE1) in NHRF.” PMID 25496504 Dec 2014
Known as Misodel “vaginal slow release misoprostol (Misodel®)” NCT02918110
Known as misopristol ClinicalTrials.gov intervention name — accepted as the source's own label NCT01600612
Known as Misoprostol (Cytotec) Misoprostol (Cytotec)NCT01933360
Known as Misoprostol is also known as Cytotec Misoprostol is also known as CytotecNCT01916681
Known as Misoprostol Vaginal Insert Misoprostol Vaginal Insert (MVI 100)” NCT00528255
Known as Misotac “In the misoprostol group (n = 183), sublingual misoprostol was given by putting two moistened tablets of misoprostol (400 µg) under the tongue and allowing them to dissolve...” NCT01466530
12

“Women will receive vaginally one tablet misoprostol 200 mcg(Misotac; Sigma Pharma, SAE, EGYPT) plus one tablet isosorbide mononitrate 40 mg(Effox 40 mg; Minapharm).” NCT03587077

“misoprostol (misotac® sigma pharmaceutical industries) 200 mcg vaginally applied ten and four hours prior to the second attempt of IUD insertion” NCT03790371

“Misoprostol group (M) received 2 rectal misoprostol tablets (800 μg) (Misotac; SIGMA Pharm, Cairo, Egypt) after the delivery of the baby.” NCT03556852

“women will receive misoprostol 100 mcg (Misotac, Sigma Pharmaceuticals, Egypt) vaginally applied every 6 hours till cervical dilatation.” NCT03584698

“1 vaginal tablet of misoprostol (200mcg) (Misotac®; Sigma Pharma, SAE, Egypt) inserted by the study nurse 3 hours before IUD insertion.” NCT04080336

“the women will be received two tablets of misoprostol 400 mcg vaginally before IUD removal (Misotac®; Sigma Pharma, SAE, Egypt).” NCT03600064

“800μg rectal misoprostol (Misotac®, SIGMA, Egypt) immediately after urinary catheterization and before skin incision” NCT04635007

“received misoprostol 800 µg (Misotac 200 µg tablets, SIGMA pharmaceutical) once dose vaginally” NCT03148561

“1 vaginal tablet of misoprostol (200 mcg) (Misotac®; Sigma Pharma, SAE, Egypt)” NCT04080349

“two intrauterine misoprostol tablets (Misotac® 200microgram, Sigma Ph., Egypt)” NCT06364098

“800 µg of misoprostol (Misotac 200 µg Sigma for Pharmaceutical Industries)” NCT02573051

“treat patients with isthmocele with misotac.” NCT04579965

Known as Misotac (Misoprostol) Misotac (Misoprostol)NCT02036437
Known as Misotac 200 µg tablets “received misoprostol 800 µg (Misotac 200 µg tablets, SIGMA pharmaceutical) once dose sublingually” NCT05088720
Known as MVI “Women enrolled into the Phase III trial, EXPEDITE (clinical trial registration: NCT01127581), had labour induced with either a misoprostol or dinoprostone vaginal insert (MVI or DVI).” PMID 25758619 Mar 2015
Known as MVI 100 “Misoprostol Vaginal Insert (MVI 100)” NCT00528255
Known as PGE1 “intravenous form of Prostaglandin E1 (PGE1)” NCT00598429
4

“misoprostol (PGE1) 200ug” NCT02738177

NCT07604051

NCT01467076

NCT02223949

Known as Prostaglandin E1 “intravenous injection of prostaglandin E1 20 ug per day during hospitalization period” NCT01108120
5

“PGE1 (Prostaglandin E1) tablet is inserted in the posterior fornix” NCT02223949

NCT00955929

NCT07503184

NCT00733434

NCT00598429

Known as Prostaglandin E2 “Introduction: The study aimed to investigate the effectiveness of a single versus double dose of Prostaglandin E2 "Misoprostol, 400 microgram" during myomectomy for multiple...” NCT02154932
Known as Vagiprost “Pregnant women had taken misoprostol (vagiprost vaginal tablet; Adwia Pharmaceutical Company) vaginally as 25 micro gram of misoprostol.” NCT04514770
2

“vaginal misoprostol 25 μg (Vagiprost) tablets with vaginal estradiol 150 ml cream will be applied for induction of laour” NCT05306405

“followed by intravaginal 25mcg of misoprostol (Vagiprost)” NCT03523754

Modality Other / unclassified “misoprostol, an orally active prostaglandin” PMID 21130990 Dec 2010
Route Oral “misoprostol administered orally during the third stage of labor” NCT00097123