drugset / Trial / NCT04604366

Comparison of Vaginal Versus Sublingual Misoprostol in the Treatment of First Trimester Missed Miscarriage

NCT04604366

Phase 2 Completed 120 enrolled Islamabad Medical and Dental College
RandomizedParallel-groupSingle-blindTreatment

Summary

The miscarriage is one of the adverse outcomes of pregnancy and is responsible for stress and anxiety of the couple. there are different types of miscarriages.missed miscarriage also known as early fetal demise is one of the type of miscarriage in which patient is mostly asymptomatic but Ultrasound shows absent fetal cardiac activity.Traditionally surgical evacuation of uterus was the treatment of choice for miscarriage.The treatment of miscarriage has evolved significantly in recent years.medical management using misoprostol is the newest treatment option.Misoprostol is a synthetic prostaglandin E(1) analogue that is commonly used for medical miscarriage It can be given orally, vaginally and sublingually.

Timeline

Start
2020-11-02
Primary completion
2021-12-15
Completion
2021-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Misoprostol Other / unclassified 600 ug Intravenous
Subject Misoprostol Other / unclassified 800 ug Intravenous