drugset / Trial / NCT05532215

Sublingual Misoprostol in Reduction of Caesarean Blood Loss

NCT05532215

Unknown 152 enrolled OZORI EBIOGBO STANLEY
RandomizedParallel-groupQuadruple-blindPrevention

Summary

Caesarean delivery is inevitably associated with a higher amount of blood loss vis-à-vis primary postpartum haemorrhage, when compared to vaginal delivery. Oxytocin use in tropical developing countries for the reduction blood loss at caesarean section have been met with challenges of ineffectiveness due to poor transportation, inadequate storage and drug adulteration. Therefore, there is a need for an effective, temperature stable uterotonic with a lesser risk of adulteration. The study is aimed at evaluating the effectiveness and safety of adjunctive sublingual misoprostol in reducing intraoperative blood loss at caesarean section.

Timeline

Start
2023-03-14
Primary completion
2023-10-14
Completion
2023-11-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Misoprostol Other / unclassified 400 ug Subcutaneous
Background Oxytocin Peptide 20 iu Intravenous

Indications

No indication recorded.