drugset / Trial / NCT05532215
Sublingual Misoprostol in Reduction of Caesarean Blood Loss
RandomizedParallel-groupQuadruple-blindPrevention
Summary
Caesarean delivery is inevitably associated with a higher amount of blood loss vis-à-vis primary postpartum haemorrhage, when compared to vaginal delivery. Oxytocin use in tropical developing countries for the reduction blood loss at caesarean section have been met with challenges of ineffectiveness due to poor transportation, inadequate storage and drug adulteration. Therefore, there is a need for an effective, temperature stable uterotonic with a lesser risk of adulteration. The study is aimed at evaluating the effectiveness and safety of adjunctive sublingual misoprostol in reducing intraoperative blood loss at caesarean section.
Timeline
- Start
- 2023-03-14
- Primary completion
- 2023-10-14
- Completion
- 2023-11-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Misoprostol | Other / unclassified | 400 ug | Subcutaneous |
| Background | Oxytocin | Peptide | 20 iu | Intravenous |
Indications
No indication recorded.