Impact of Misoprostol on Blood Loss In Myomectomy Operations

NCT02061657 ↗

Phase 3 Completed 50 enrolled Ain Shams University

RandomizedParallel-groupDouble-blindPrevention

Summary

The aim of this research work is to assess the effect of using single preoperative dose of rectal misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications

Timeline

Start: 2013-06
Primary completion: 2014-06
Completion: 2014-07

Outcome

Met primary endpoint

paper Intra-operative blood loss was significantly lower in those women randomised to receive rectal misoprostol versus the placebo group PMID 26174128 ↗

Publications

Abdel-Hafeez M, Elnaggar A, Ali M, Ismail AM, Yacoub M. Rectal misoprostol for myomectomy: A randomised placebo-controlled study. Aust N Z J Obstet Gynaecol. 2015 Aug;55(4):363-8. doi: 10.1111/ajo.12359. Epub 2015 Jul 14.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Misoprostol	Other / unclassified	400 ug	Rectal