drugset / Trial / NCT01271257
Pharmacokinetics of Misoprostol With Titrated Oral Administration
Non-randomizedSingle-groupOpen-labelBasic science
Summary
The AUC240, AUC360, and AUC480 of titrated oral misoprostol are greater than traditional oral misoprostol.
Timeline
- Start
- 2011-01
- Primary completion
- 2014-12
- Completion
- 2014-12
Publications
- Background Tang OS, Schweer H, Seyberth HW, Lee SW, Ho PC. Pharmacokinetics of different routes of administration of misoprostol. Hum Reprod. 2002 Feb;17(2):332-6. doi: 10.1093/humrep/17.2.332.
- Background Zieman M, Fong SK, Benowitz NL, Banskter D, Darney PD. Absorption kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol. 1997 Jul;90(1):88-92. doi: 10.1016/S0029-7844(97)00111-7.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Misoprostol | Other / unclassified | 20 ug | Oral |
| Subject | Misoprostol | Other / unclassified | 80 ug | Oral |
Indications
No indication recorded.