Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage

Phase 1 Completed 400 enrolled Hormozgan University of Medical Sciences

RandomizedParallel-groupDouble-blindPrevention

Summary

Post partum Hemorrhage (PPH) is one of three main causes of death in pregnant women. Oxytocin is widely used for prevention of PPH. Some studies suggested misoprostol as an alternative treatment when Oxytocin isn't available. The aim of this study is to compare the safety and efficacy of Oxytocin and misoprostol for prevention of PPH.

Timeline

Start: 2013-05
Primary completion: 2013-12
Completion: 2013-12

Publications

Rajaei M, Karimi S, Shahboodaghi Z, Mahboobi H, Khorgoei T, Rajaei F. Safety and efficacy of misoprostol versus oxytocin for the prevention of postpartum hemorrhage. J Pregnancy. 2014;2014:713879. doi: 10.1155/2014/713879. Epub 2014 Mar 5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Misoprostol	Other / unclassified	400 ug	Oral
Comparator	Oxytocin	Peptide	20 iu	—

Indications

No indication recorded.