Comparison Between Vaginal and Sublingual Misoprostol 50 µg for Cervical Ripening Prior to Induction of Labor

Summary

To analyze whether there is a statistically significant difference in the modifications present in the uterine cervix 6 hours after administration of misoprostol 50 µg through vaginal versus sublingual routes.

Timeline

Start

2014-10

Primary completion

2015-05

Completion

2016-01

Outcome

Missed primary endpoint

paper There was no significant difference for the mean and standard deviation for Bishop score for sublingual and vaginal route (P = 0.761). PMID 28204882 ↗

Publications

• Conde A, Ben S, Tarigo J, Artucio S, Varela V, Grimaldi P, Sosa C, Alonso J. Comparison between vaginal and sublingual misoprostol 50 microg for cervical ripening prior to induction of labor: randomized clinical trial. Arch Gynecol Obstet. 2017 Apr;295(4):839-844. doi: 10.1007/s00404-017-4297-9. Epub 2017 Feb 16.

Drugs

Indications